Synthesis and cytostatic properties of daunorubicin derivatives, containing N-phenylthiourea or N-ethylthiourea moieties in the 3'-position.

Solvatochromic Properties of Heteroleptic Copper(II) Complexes Containing N,N,N',N'-Tetramethylethylenediamine and 2-Aacetylcyclopentanone Ligands

Three new heteroleptic copper(II) complexes, [(tmen)Cu(dike)H2O]X where tmen = N,N,N',N'-tetramethylethylenediamine, dike = 2-acetylcyclopentanone anion and X= ClO4- (1), Cl- (2) and Br- (3) are prepared and characterized by elemental analyses, molar conductance measurements and IR and UV-Vis spectroscopy techniques. The complex 1 is fairly soluble in various organic solvents and demonstrates d...

design and synthesis of novel oxindol derivatives with n-benzylpiperidine and n-benzylpiperazine moieties as cholinesterases inhibitors

Design, synthesis, biological activities and 3D-QSAR of new N,N'-diacylhydrazines containing 2,4-dichlorophenoxy moieties.

A series of new N,N'-diacylhydrazine derivatives were designed and synthesized. Their structures were verified by 1H-NMR, MS and elemental analysis. The herbicidal activities and plant growth regulating activity of these N,N'-diacylhydrazines were evaluated. The herbicidal activity results showed that most of these N,N'-diacyl-hydrazines showed excellent in vivo activities against Echinochloa c...

Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N-Diethyl-Substituted Amido Moieties

Sulfonamide drugs which have brought about an antibiotic revolution in medicine are associated with a wide range of biological activities. We have synthesized a series of α-tolylsulfonamide, 1-11 and their substituted N,N-diethyl-2-(phenylmethylsulfonamido) alkanamide derivatives, 12-22 in improved and excellent yields in aqueous medium at room temperature through highly economical synthetic ro...

Application of Poly(N, N′- dibromo-N-ethyl-naphthyl-2,7-disulfonamide) for the Regioselective Synthesis of New 3-Sulfenyl Indole Derivatives

Electron-rich aza-aromatic compounds such as indoles is structures of particular interest and importancein organic chemistry. A useful procedure for the preparation of new 3-sulfenyl indole derivatives using S-alkyl or S-arylthiophthalimides as sulfenylating agents and poly(N, N′-dibromo-N-ethyl-naphthyl-2,7-disulfonamide) as novel catalyst is described. The method represents an efficient prepa...